GDF-15 contributes to proliferation and immune escape of malignant gliomas


Autoria(s): Roth, Patrick; Junker, Markus; Tritschler, Isabel; Mittelbronn, Michel; Dombrowski, Yvonne; Breit, Samuel N; Tabatabai, Ghazaleh; Wick, Wolfgang; Weller, Michael; Wischhusen, Jörg
Data(s)

01/08/2010

Resumo

Growth and differentiation factor (GDF)-15 is a member of the transforming growth factor (TGF)-beta family. GDF-15 is necessary for the maintenance of pregnancy but has also been linked to other physiologic and pathologic conditions.

Identificador

http://pure.qub.ac.uk/portal/en/publications/gdf15-contributes-to-proliferation-and-immune-escape-of-malignant-gliomas(508fb042-1627-4045-8ad8-039cb7a05243).html

http://dx.doi.org/10.1158/1078-0432.CCR-10-0705

Idioma(s)

eng

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Roth , P , Junker , M , Tritschler , I , Mittelbronn , M , Dombrowski , Y , Breit , S N , Tabatabai , G , Wick , W , Weller , M & Wischhusen , J 2010 , ' GDF-15 contributes to proliferation and immune escape of malignant gliomas ' Clinical Cancer Research , vol 16 , no. 15 , pp. 3851-9 . DOI: 10.1158/1078-0432.CCR-10-0705

Palavras-Chave #Animals #Blotting, Western #Brain Neoplasms #Cell Line, Tumor #Cell Proliferation #Cytotoxicity, Immunologic #Enzyme-Linked Immunosorbent Assay #Glioma #Growth Differentiation Factor 15 #Humans #Immunohistochemistry #Mice #RNA, Small Interfering #Reverse Transcriptase Polymerase Chain Reaction #Tumor Escape
Tipo

article