GWAS identifies an NAT2 acetylator status tag single nucleotide polymorphism to be a major locus for skin fluorescence
| Data(s) |
17/06/2014
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| Resumo |
Skin fluorescence (SF) is a non-invasive marker of AGEs and is associated with the long-term complications of diabetes. SF increases with age and is also greater among individuals with diabetes. A familial correlation of SF suggests that genetics may play a role. We therefore performed parallel genome-wide association studies of SF in two cohorts. |
| Identificador | |
| Idioma(s) |
eng |
| Direitos |
info:eu-repo/semantics/restrictedAccess |
| Fonte |
Eny , K M , Lutgers , H L , Maynard , J , Klein , B E K , Lee , K E , Atzmon , G , Monnier , V M , van Vliet-Ostaptchouk , J V , Graaff , R , van der Harst , P , Snieder , H , van der Klauw , M M , Sell , D R , Hosseini , S M , Cleary , P A , Braffett , B H , Orchard , T J , Lyons , T J , Howard , K , Klein , R , Crandall , J P , Barzilai , N , Milman , S , Ben-Avraham , D , Wolffenbuttel , B H R , Paterson , A D & LifeLines Cohort Study Group 2014 , ' GWAS identifies an NAT2 acetylator status tag single nucleotide polymorphism to be a major locus for skin fluorescence ' Diabetologia . DOI: 10.1007/s00125-014-3286-9 |
| Tipo |
article |
