Caveolin-1 single nucleotide polymorphism in antineutrophil cytoplasmic antibody associated vasculitis
| Data(s) |
2013
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| Resumo |
Immunosuppression is cornerstone treatment of antineutrophil cytoplasmic antibody associated vasculitis (AAV) but is later complicated by infection, cancer, cardiovascular and chronic kidney disease. Caveolin-1 is an essential structural protein for small cell membrane invaginations known as caveolae. Its functional role has been associated with these complications. For the first time, caveolin-1 (CAV1) gene variation is studied in AAV. |
| Identificador | |
| Idioma(s) |
eng |
| Direitos |
info:eu-repo/semantics/restrictedAccess |
| Fonte |
Chand , S , Holle , J U , Hilhorst , M , Simmonds , M J , Smith , S , Kamesh , L , Hewins , P , McKnight , A J , Maxwell , A P , Cohen Tervaert , J W , Wieczorek , S , Harper , L & Borrows , R 2013 , ' Caveolin-1 single nucleotide polymorphism in antineutrophil cytoplasmic antibody associated vasculitis ' PloS one , vol 8 , no. 7 , pp. e69022 . DOI: 10.1371/journal.pone.0069022 |
| Tipo |
article |
