Nephropathy in a hypercholesterolemic mouse model with streptozotocin-induced diabetes


Autoria(s): Hammad, Samar M; Hazen-Martin, Debra J; Sohn, Mimi; Eldridge, Leslie; Powell-Braxton, Lyn; Won, Wesley; Lyons, Timothy J
Data(s)

2003

Resumo

The contribution of preexisting hypercholesterolemia to diabetic nephropathy remains unclear. We assessed the impact of hypercholesterolemia on diabetic nephropathy using a double knockout (DKO) mouse, null for the low-density lipoprotein receptor (LDLRNDASH;/NDASH;) and the apoB mRNA editing catalytic polypeptide 1 (APOBEC1NDASH;/NDASH;).

Identificador

http://pure.qub.ac.uk/portal/en/publications/nephropathy-in-a-hypercholesterolemic-mouse-model-with-streptozotocininduced-diabetes(0b24bbe5-e9a7-40ed-ad31-811126ca49b0).html

http://dx.doi.org/73942

Idioma(s)

eng

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Hammad , S M , Hazen-Martin , D J , Sohn , M , Eldridge , L , Powell-Braxton , L , Won , W & Lyons , T J 2003 , ' Nephropathy in a hypercholesterolemic mouse model with streptozotocin-induced diabetes ' Kidney & blood pressure research , vol 26 , no. 5-6 , pp. 351-61 . DOI: 73942

Palavras-Chave #Albuminuria #Animals #Arteriosclerosis #Basement Membrane #Collagen #Cytidine Deaminase #Diabetes Mellitus, Experimental #Diabetic Nephropathies #Disease Models, Animal #Hypercholesterolemia #Kidney #Kidney Tubules #Lipid Metabolism #Lipids #Male #Mice #Mice, Knockout #Microscopy, Electron #Receptors, LDL #Streptozocin
Tipo

article