Increased serum pigment epithelium-derived factor is associated with microvascular complications, vascular stiffness and inflammation in Type 1 diabetes


Autoria(s): Jenkins, A J; Zhang, S X; Rowley, K G; Karschimkus, C S; Nelson, C L; Chung, J S; O'Neal, D N; Januszewski, A S; Croft, K D; Mori, T A; Dragicevic, G; Harper, C A; Best, J D; Lyons, T J; Ma, J-X
Data(s)

01/12/2007

Resumo

To determine in Type 1 diabetes patients if levels of pigment epithelium-derived factor (PEDF), an anti-angiogenic, anti-inflammatory and antioxidant factor, are increased in individuals with complications and positively related to vascular and renal dysfunction, body mass index, glycated haemoglobin, lipids, inflammation and oxidative stress.

Identificador

http://pure.qub.ac.uk/portal/en/publications/increased-serum-pigment-epitheliumderived-factor-is-associated-with-microvascular-complications-vascular-stiffness-and-inflammation-in-type-1-diabetes(bdaf51ed-1e72-41e2-9c15-01d0850eb79d).html

http://dx.doi.org/10.1111/j.1464-5491.2007.02281.x

Idioma(s)

eng

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Jenkins , A J , Zhang , S X , Rowley , K G , Karschimkus , C S , Nelson , C L , Chung , J S , O'Neal , D N , Januszewski , A S , Croft , K D , Mori , T A , Dragicevic , G , Harper , C A , Best , J D , Lyons , T J & Ma , J-X 2007 , ' Increased serum pigment epithelium-derived factor is associated with microvascular complications, vascular stiffness and inflammation in Type 1 diabetes ' Diabetic Medicine , vol 24 , no. 12 , pp. 1345-51 . DOI: 10.1111/j.1464-5491.2007.02281.x

Palavras-Chave #Adult #Biological Markers #Body Mass Index #C-Reactive Protein #Cross-Sectional Studies #Diabetes Mellitus, Type 1 #Diabetic Nephropathies #Diabetic Retinopathy #Enzyme-Linked Immunosorbent Assay #Eye Proteins #Female #Hemoglobin A, Glycosylated #Humans #Male #Middle Aged #Nerve Growth Factors #Oxidative Stress #Protease Inhibitors #Serpins
Tipo

article