Oxidative and endoplasmic reticulum stresses mediate apoptosis induced by modified LDL in human retinal Müller cells
| Data(s) |
01/07/2012
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| Resumo |
We previously showed that extravasated, modified LDL is implicated in pericyte loss in diabetic retinopathy (DR). Here, we investigate whether modified LDL induces apoptosis in retinal Müller glial cells. |
| Identificador | |
| Idioma(s) |
eng |
| Direitos |
info:eu-repo/semantics/restrictedAccess |
| Fonte |
Wu , M , Yang , S , Elliott , M H , Fu , D , Wilson , K , Zhang , J , Du , M , Chen , J & Lyons , T 2012 , ' Oxidative and endoplasmic reticulum stresses mediate apoptosis induced by modified LDL in human retinal Müller cells ' Investigative ophthalmology & visual science , vol 53 , no. 8 , pp. 4595-604 . DOI: 10.1167/iovs.12-9910 |
| Palavras-Chave | #Adult #Apoptosis #Blotting, Western #Cell Survival #Cells, Cultured #Diabetic Retinopathy #Endoplasmic Reticulum #Endoplasmic Reticulum Stress #Female #Glycosylation #Humans #In Situ Nick-End Labeling #Lipoproteins, LDL #Male #Middle Aged #Neuroglia #Oxidation-Reduction #Oxidative Stress #Retinal Ganglion Cells #Young Adult #/dk/atira/pure/subjectarea/asjc/2700/2731 #Ophthalmology #/dk/atira/pure/subjectarea/asjc/2800/2809 #Sensory Systems #/dk/atira/pure/subjectarea/asjc/2800/2804 #Cellular and Molecular Neuroscience #/dk/atira/pure/subjectarea/asjc/2700 #Medicine(all) |
| Tipo |
article |
