RUNX3 functions as an oncogene in ovarian cancer


Autoria(s): Lee, Cecilia Wei Lin; Chuang, Linda Shyue Huey; Kimura, Shunichi; Lai, Soak Kuan; Ong, Chee Wee; Yan, Benedict; Salto-Tellez, Manuel; Choolani, Mahesh; Ito, Yoshiaki
Data(s)

01/08/2011

Resumo

The Runt domain transcription factor, RUNX3, has been shown to be a tumor suppressor in a variety of cancers including gastric, colon and breast cancer. Interestingly, an oncogenic role for RUNX3 has also been suggested in basal cell carcinoma and head and neck cancer. Here, we explore the role of RUNX3 in ovarian cancer.

Identificador

http://pure.qub.ac.uk/portal/en/publications/runx3-functions-as-an-oncogene-in-ovarian-cancer(51071f25-52ea-44d2-a86e-3f516cf9af64).html

http://dx.doi.org/10.1016/j.ygyno.2011.04.044

Idioma(s)

eng

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Lee , C W L , Chuang , L S H , Kimura , S , Lai , S K , Ong , C W , Yan , B , Salto-Tellez , M , Choolani , M & Ito , Y 2011 , ' RUNX3 functions as an oncogene in ovarian cancer ' Gynecologic Oncology , vol 122 , no. 2 , pp. 410-7 . DOI: 10.1016/j.ygyno.2011.04.044

Palavras-Chave #Gene Expression Profiling #Ovarian Neoplasms #Oncogenes #Humans #Core Binding Factor Alpha 3 Subunit #Cell Line, Tumor #Female
Tipo

article