Dual-colour HER2/chromosome 17 chromogenic in situ hybridisation enables accurate assessment of HER2 genomic status in ovarian tumours


Autoria(s): Yan, Benedict; Choo, Shoa Nian; Mulyadi, Patricia; Srivastava, Supriya; Ong, Chee Wee; Yong, Kol Jia; Putti, Thomas; Salto-Tellez, Manuel; Lim, Gkeok Stzuan Diana
Data(s)

01/12/2011

Resumo

Ovarian cancer is a leading cause of gynaecological cancer-related morbidity and mortality. There has been increasing interest in the potential utility of anti-human epidermal growth factor receptor 2 (anti-HER2) agents in the treatment of this disease, with the attendant need to identify suitable predictive biomarkers of response to treatment.

Identificador

http://pure.qub.ac.uk/portal/en/publications/dualcolour-her2chromosome-17-chromogenic-in-situ-hybridisation-enables-accurate-assessment-of-her2-genomic-status-in-ovarian-tumours(409c9298-6597-4d21-baf3-76f99311a1c4).html

http://dx.doi.org/10.1136/jclinpath-2011-200082

Idioma(s)

eng

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Yan , B , Choo , S N , Mulyadi , P , Srivastava , S , Ong , C W , Yong , K J , Putti , T , Salto-Tellez , M & Lim , G S D 2011 , ' Dual-colour HER2/chromosome 17 chromogenic in situ hybridisation enables accurate assessment of HER2 genomic status in ovarian tumours ' Journal of Clinical Pathology , vol 64 , no. 12 , pp. 1097-101 . DOI: 10.1136/jclinpath-2011-200082

Palavras-Chave #Sensitivity and Specificity #Chromosomes, Human, Pair 17 #Ovarian Neoplasms #Genes, erbB-2 #Receptor, erbB-2 #Humans #Color #Gene Amplification #In Situ Hybridization #Adenocarcinoma, Mucinous #Cohort Studies #Immunohistochemistry #Female
Tipo

article