HLA antigen frequencies and Wegener's granulomatosis


Autoria(s): Murty, G E; Mains, B T; Middleton, D; Maxwell, A P; Savage, D A
Data(s)

1991

Resumo

Previous reports of an association between HLA tissue type and Wegener's granulomatosis are contradictory. By using for the first time a highly sensitive restriction fragment-length polymorphism (RFLP) analysis in addition to standard microcytotoxicity assays, the largest series yet investigated (41 patients) was tissue typed. No association was found between any specific HLA antigen and Wegener's granulomatosis. Although the condition appears to be immunologically mediated, this study indicates that the HLA antigens do not have a major role.

Identificador

http://pure.qub.ac.uk/portal/en/publications/hla-antigen-frequencies-and-wegeners-granulomatosis(0484883c-30c3-439b-b19f-a0d74b902f7a).html

Idioma(s)

eng

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Murty , G E , Mains , B T , Middleton , D , Maxwell , A P & Savage , D A 1991 , ' HLA antigen frequencies and Wegener's granulomatosis ' Clinical otolaryngology and allied sciences , vol 16 , no. 5 , pp. 448-51 .

Tipo

article