No consistent evidence for association between mtDNA variants and Alzheimer disease


Autoria(s): Hudson, G; Sims, R; Harold, D; Chapman, J; Hollingworth, P; Gerrish, A; Russo, G; Hamshere, M; Moskvina, V; Jones, N; Thomas, C; Stretton, A; Holmans, P A; O'Donovan, M C; Owen, M J; Williams, J; Chinnery, P F; GERAD1 Consortium; Passmore, Peter
Data(s)

03/04/2012

Resumo

Although several studies have described an association between Alzheimer disease (AD) and genetic variation of mitochondrial DNA (mtDNA), each has implicated different mtDNA variants, so the role of mtDNA in the etiology of AD remains uncertain.

Identificador

http://pure.qub.ac.uk/portal/en/publications/no-consistent-evidence-for-association-between-mtdna-variants-and-alzheimer-disease(43e8de03-6919-4806-9224-c71bae16b792).html

http://dx.doi.org/10.1212/WNL.0b013e31824e8f1d

Idioma(s)

eng

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Hudson , G , Sims , R , Harold , D , Chapman , J , Hollingworth , P , Gerrish , A , Russo , G , Hamshere , M , Moskvina , V , Jones , N , Thomas , C , Stretton , A , Holmans , P A , O'Donovan , M C , Owen , M J , Williams , J , Chinnery , P F , GERAD1 Consortium & Passmore , P 2012 , ' No consistent evidence for association between mtDNA variants and Alzheimer disease ' Neurology , vol 78 , no. 14 , pp. 1038-42 . DOI: 10.1212/WNL.0b013e31824e8f1d

Palavras-Chave #/dk/atira/pure/subjectarea/asjc/2700/2728 #Clinical Neurology #/dk/atira/pure/subjectarea/asjc/1200/1201 #Arts and Humanities (miscellaneous)
Tipo

article