Safety and efficacy of a CXCR2 antagonist in patients with severe asthma and sputum neutrophils:a randomized, placebo-controlled clinical trial


Autoria(s): Nair, P; Gaga, M; Zervas, E; Alagha, K; Hargreave, F E; O'Byrne, P M; Stryszak, P; Gann, L; Sadeh, J; Chanez, P; Study Investigators; Heaney, Liam
Data(s)

01/07/2012

Resumo

Increased numbers of neutrophils are reported in the airways of patients with severe asthma. It is not clear if they contribute to the lack of control and severity. There are currently no strategies to investigate this by decreasing neutrophil numbers in the airways.

Identificador

http://pure.qub.ac.uk/portal/en/publications/safety-and-efficacy-of-a-cxcr2-antagonist-in-patients-with-severe-asthma-and-sputum-neutrophils(9d875d38-d8ea-4fe3-a36a-9e0efd35922a).html

http://dx.doi.org/10.1111/j.1365-2222.2012.04014.x

Idioma(s)

eng

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Nair , P , Gaga , M , Zervas , E , Alagha , K , Hargreave , F E , O'Byrne , P M , Stryszak , P , Gann , L , Sadeh , J , Chanez , P , Study Investigators & Heaney , L 2012 , ' Safety and efficacy of a CXCR2 antagonist in patients with severe asthma and sputum neutrophils : a randomized, placebo-controlled clinical trial ' Clinical & Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology , vol 42 , no. 7 , pp. 1097-103 . DOI: 10.1111/j.1365-2222.2012.04014.x

Palavras-Chave #/dk/atira/pure/subjectarea/asjc/2400/2403 #Immunology #/dk/atira/pure/subjectarea/asjc/2700/2723 #Immunology and Allergy
Tipo

article