A click chemistry approach to C3 symmetric, G-quadruplex stabilising ligands.

Autoria(s): Moses, J.E.; Ritson, D.J.; Zhang, F.; Lombardo, C.M.; Haider, Shozeb; Oldham, N.; Neidle, S.
Data(s)

28/06/2010
Resumo

Described is the structure-based design and synthesis of a series of tris-triazole G-quadruplex binding ligands utilising the copper catalysed azide–alkyne ‘click’ reaction. The results of G-quadruplex stabilisation by the ligands are reported and discussed.
Identificador

http://pure.qub.ac.uk/portal/en/publications/a-click-chemistry-approach-to-c3-symmetric-gquadruplex-stabilising-ligands(2f40d490-ef4f-429e-87bf-1d9882f145c4).html

http://dx.doi.org/10.1039/c005055e
Idioma(s)

eng
Direitos

info:eu-repo/semantics/restrictedAccess
Fonte

Moses , J E , Ritson , D J , Zhang , F , Lombardo , C M , Haider , S , Oldham , N & Neidle , S 2010 , ' A click chemistry approach to C3 symmetric, G-quadruplex stabilising ligands. ' Organic and Biomolecular Chemistry , vol 8(13) , no. 13 , pp. 2926-2930 . DOI: 10.1039/c005055e
Palavras-Chave #/dk/atira/pure/subjectarea/asjc/1300/1303 #Biochemistry #/dk/atira/pure/subjectarea/asjc/1600/1605 #Organic Chemistry #/dk/atira/pure/subjectarea/asjc/1600/1606 #Physical and Theoretical Chemistry
Tipo

article
Acesso ao item digital