Tissue microarrays characterise the clinical significance of a VEGF-A protein expression signature in gastrointestinal stromal tumours


Autoria(s): Salto-Tellez, Manuel; Nga, M.E.; Han, H.C.; Wong, A.S.C.; Lee, C.K.; Anuar, D.; Ng, S.S.; Ho, M.; Wee, A.; Chan, Y.H.; Soong, R.
Data(s)

12/03/2007

Resumo

A tissue microarray analysis of 22 proteins in gastrointestinal stromal tumours ( GIST), followed by an unsupervised, hierarchical monothetic cluster statistical analysis of the results, allowed us to detect a vascular endothelial growth factor ( VEGF) protein overexpression signature discriminator of prognosis in GIST, and discover novel VEGF-A DNA variants that may have functional significance.

Identificador

http://pure.qub.ac.uk/portal/en/publications/tissue-microarrays-characterise-the-clinical-significance-of-a-vegfa-protein-expression-signature-in-gastrointestinal-stromal-tumours(8f7adda8-70fc-4605-96e0-7a1dc6b53131).html

http://dx.doi.org/10.1038/sj.bjc.6603551

Idioma(s)

eng

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Salto-Tellez , M , Nga , M E , Han , H C , Wong , A S C , Lee , C K , Anuar , D , Ng , S S , Ho , M , Wee , A , Chan , Y H & Soong , R 2007 , ' Tissue microarrays characterise the clinical significance of a VEGF-A protein expression signature in gastrointestinal stromal tumours ' British Journal of Cancer , vol 96 , no. 5 , pp. 776-782 . DOI: 10.1038/sj.bjc.6603551

Palavras-Chave #/dk/atira/pure/subjectarea/asjc/1300/1306 #Cancer Research #/dk/atira/pure/subjectarea/asjc/2700/2730 #Oncology
Tipo

article