Complement Component 3: an assessment of association with AMD and analysis of gene-gene and gene-environment interactions in a Northern Irish cohort


Autoria(s): Mckay, G.J.; Dasari, Shilpa; Patterson, Christopher; Chakravarthy, Usha; Silvestri, Giuliana
Data(s)

01/03/2010

Resumo

Purpose: A non-synonymous single nucleotide polymorphism ( SNP) in complement component 3 has been shown to increase the risk of age-related macular degeneration (AMD). We assess its effect on AMD risk in a Northern Irish sample, test for gene-gene and gene-environment interaction, and review a risk prediction model.

Formato

application/pdf

Identificador

http://pure.qub.ac.uk/portal/en/publications/complement-component-3-an-assessment-of-association-with-amd-and-analysis-of-genegene-and-geneenvironment-interactions-in-a-northern-irish-cohort(bf1492b0-5862-49ab-b824-be1fa2d6e13e).html

http://pure.qub.ac.uk/ws/files/8212084/Complement%20component.pdf

http://www.scopus.com/inward/record.url?scp=77949327478&partnerID=8YFLogxK

Idioma(s)

eng

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Mckay , G J , Dasari , S , Patterson , C , Chakravarthy , U & Silvestri , G 2010 , ' Complement Component 3: an assessment of association with AMD and analysis of gene-gene and gene-environment interactions in a Northern Irish cohort ' Molecular Vision , vol 16 , pp. 194-199 .

Palavras-Chave #/dk/atira/pure/subjectarea/asjc/2700/2731 #Ophthalmology
Tipo

article