Hypercapnic acidosis attenuates pulmonary epithelial wound repair by an NF-kappa B dependent mechanism
| Data(s) |
01/11/2009
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|---|---|
| Resumo |
Background: Hypercapnic acidosis exerts protective effects in acute lung injury but may also slow cellular repair. These effects may be mediated via inhibition of nuclear factor-kappa B (NF-kappa B), a pivotal transcriptional regulator in inflammation and repair. |
| Identificador |
http://dx.doi.org/10.1136/thx.2008.110304 http://www.scopus.com/inward/record.url?scp=72549102010&partnerID=8YFLogxK |
| Idioma(s) |
eng |
| Direitos |
info:eu-repo/semantics/restrictedAccess |
| Fonte |
O'Toole , D , Hassett , P , Contreras , M , Higgins , B D , McKeown , S , McAuley , D , O'Brien , T & Laffey , J G 2009 , ' Hypercapnic acidosis attenuates pulmonary epithelial wound repair by an NF-kappa B dependent mechanism ' Thorax , vol 64 , no. 11 , pp. 976-982 . DOI: 10.1136/thx.2008.110304 |
| Palavras-Chave | #/dk/atira/pure/subjectarea/asjc/2700/2740 #Pulmonary and Respiratory Medicine |
| Tipo |
article |
