Intensity-modulated radiotherapy reduces lung irradiation in patients with carcinoma of the oesophagus.
Data(s) |
2002
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Resumo |
The 2-year survival rate after conventional radiotherapy for carcinoma of the oesophagus is around 10–20% [8]. Concomitant chemoradiation schedules have produced survival figures of 25–30% at 5 years, and this is now considered standard treatment [1]. Conformal radiotherapy techniques offer the potential to deliver higher doses of radiation to oesophageal tumours [5], and this may improve local tumour control. However, concerns regarding late normal tissue damage to the lung parenchyma and spinal cord remain a concern. Intensitymodulated radiotherapy (IMRT) allows complex dose distributions to be produced, and can reduce the dose to radiosensitive organs close to the tumour [2]. The present study was designed to investigate the impact of beam intensity modulation on treatment planning for carcinoma of the oesophagus, by comparing a standard three-dimensional conformal radiotherapy (3DCRT) technique to an IMRT technique using the same number and orientation of treatment fields. |
Identificador |
http://dx.doi.org/10.1159/000061308 http://www.scopus.com/inward/record.url?scp=0036134329&partnerID=8YFLogxK |
Idioma(s) |
eng |
Direitos |
info:eu-repo/semantics/restrictedAccess |
Fonte |
Nutting , C M , Bedford , J L , Cosgrove , V , Tait , D M , Dearnaley , D P & Webb , S 2002 , ' Intensity-modulated radiotherapy reduces lung irradiation in patients with carcinoma of the oesophagus. ' Frontiers of Radiation Therapy and Oncology , vol 37 , pp. 128-131 . DOI: 10.1159/000061308 |
Palavras-Chave | #/dk/atira/pure/subjectarea/asjc/2700 #Medicine(all) #/dk/atira/pure/subjectarea/asjc/2700/2730 #Oncology #/dk/atira/pure/subjectarea/asjc/2700/2741 #Radiology Nuclear Medicine and imaging |
Tipo |
article |