Evidence for altered ETB receptor characterisitics during development and progression of ventricular cardiomyocyte hypertrophy.
| Data(s) |
01/07/2004
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|---|---|
| Resumo |
The hypothesis that endothelin (ET) receptor mechanisms are altered during development and progression of left ventricular hypertrophy (LVH) in vivo was tested using spontaneously hypertensive rats (SHRs). Ventricular cardiomyocytes were isolated from SHRs before onset (8 and 12 wk) and during progression (16, 20, and 24 wk) of LVH and compared with age-matched normotensive Wistar-Kyoto (WKY) rats. PreproET-1 mRNA expression was elevated in SHR (P |
| Identificador |
http://dx.doi.org/10.1152/ajpheart.00461.2003 http://www.scopus.com/inward/record.url?scp=3042675140&partnerID=8YFLogxK |
| Idioma(s) |
eng |
| Direitos |
info:eu-repo/semantics/restrictedAccess |
| Fonte |
Lee , G R , Bell , D , Kelso , E , Argent , C C H & McDermott , B 2004 , ' Evidence for altered ETB receptor characterisitics during development and progression of ventricular cardiomyocyte hypertrophy. ' American Journal of Physiology - Heart and Circulatory Physiology , vol 287 , no. 1 56-1 , pp. H425-H432 . DOI: 10.1152/ajpheart.00461.2003 |
| Palavras-Chave | #/dk/atira/pure/subjectarea/asjc/1300/1314 #Physiology |
| Tipo |
article |
