Apoptosis and cell-cycle regulatory proteins in colorectal carcinoma: relationship to tumour stage and patient survival
| Data(s) |
01/08/2001
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|---|---|
| Resumo |
The quantitative assessment of apoptotic index (AI) and mitotic index (MI) and the immunoreactivity of p53, bcl-2, p21, and mdm2 were examined in tumour and adjacent normal tissue samples from 30 patients with colonic and 22 with rectal adenocarcinoma. Individual features and combined profiles were correlated with clinicopathological parameters and patient survival data to assess their prognostic value. Increased AI was significantly associated with increased bcl-2 expression (p |
| Identificador |
http://dx.doi.org/10.1002/path.894 http://www.scopus.com/inward/record.url?scp=0034860818&partnerID=8YFLogxK |
| Idioma(s) |
eng |
| Direitos |
info:eu-repo/semantics/restrictedAccess |
| Fonte |
Elkablawy , M A , Maxwell , P , Williamson , K , Anderson , N & Hamilton , P 2001 , ' Apoptosis and cell-cycle regulatory proteins in colorectal carcinoma: relationship to tumour stage and patient survival ' Journal of Pathology , vol 194(4) , no. 4 , pp. 436-443 . DOI: 10.1002/path.894 |
| Palavras-Chave | #/dk/atira/pure/subjectarea/asjc/2700/2734 #Pathology and Forensic Medicine |
| Tipo |
article |
