The influence of transforming growth factor-beta1 gene polymorphisms on the severity of gingival overgrowth associated with concomitant use of cyclosporin A and a calcium channel blocker


Autoria(s): Linden, G J; Haworth, S E; Maxwell, A P; Poulton, K V; Dyer, P A; Middleton, D; Irwin, C R; Marley, J J; McNamee, P; Short, C D; Hull, P S; James, J A
Data(s)

01/06/2001

Resumo

The purpose of this study was to determine whether the prevalence and severity of gingival overgrowth in renal transplant recipients concomitantly treated with cyclosporin and a calcium channel blocker was associated with functional polymorphisms within the signal sequence of the transforming growth factor-(TGF)beta1 gene.

Identificador

http://pure.qub.ac.uk/portal/en/publications/the-influence-of-transforming-growth-factorbeta1-gene-polymorphisms-on-the-severity-of-gingival-overgrowth-associated-with-concomitant-use-of-cyclosporin-a-and-a-calcium-channel-blocker(bcbadca5-54ac-47eb-a4e1-f53edf215f27).html

http://dx.doi.org/10.1902/jop.2001.72.6.808

http://www.scopus.com/inward/record.url?scp=0034972681&partnerID=8YFLogxK

Idioma(s)

eng

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Linden , G J , Haworth , S E , Maxwell , A P , Poulton , K V , Dyer , P A , Middleton , D , Irwin , C R , Marley , J J , McNamee , P , Short , C D , Hull , P S & James , J A 2001 , ' The influence of transforming growth factor-beta1 gene polymorphisms on the severity of gingival overgrowth associated with concomitant use of cyclosporin A and a calcium channel blocker ' Journal of Periodontology , vol 72 , no. 6 , pp. 808-814 . DOI: 10.1902/jop.2001.72.6.808

Palavras-Chave #Adult #Age Factors #Alleles #Analysis of Variance #Arginine #Calcium Channel Blockers #Chi-Square Distribution #Codon #Confidence Intervals #Cyclosporine #DNA #Female #Gene Expression Regulation #Genotype #Gingival Overgrowth #Heterozygote #Homozygote #Humans #Immunosuppressive Agents #Kidney Transplantation #Leucine #Logistic Models #Male #Odds Ratio #Polymorphism, Genetic #Proline #Transforming Growth Factor beta #Transforming Growth Factor beta1
Tipo

article