Risk stratification of latent tuberculosis defined by combined interferon gamma release assays.
| Data(s) |
2012
|
|---|---|
| Resumo |
Most individuals infected with Mycobacterium tuberculosis develop latent tuberculosis infection (LTBI). Some may progress to active disease and would benefit from preventive treatment yet no means currently exists to predict who will reactivate. Here, we provide an approach to stratify LTBI based on IFN-γ responses to two antigens, the recombinant Early-Secreted Antigen Target-6 (rESAT-6) and the latency antigen Heparin-Binding Haemagglutinin (HBHA). Journal Article Research Support, Non-U.S. Gov't info:eu-repo/semantics/published |
| Formato |
1 full-text file(s): application/pdf |
| Identificador |
uri/info:doi/10.1371/journal.pone.0043285 uri/info:pii/PONE-D-12-06489 uri/info:pmid/22912846 uri/info:pmcid/PMC3422279 https://dipot.ulb.ac.be/dspace/bitstream/2013/143596/1/PMC3422279.pdf http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/143596 |
| Idioma(s) |
en |
| Direitos |
1 full-text file(s): info:eu-repo/semantics/closedAccess |
| Fonte |
PloS one, 7 (8 |
| Palavras-Chave | #Pneumologie #Immunologie #Sciences biomédicales #Antigens, Bacterial -- immunology #Bacterial Proteins -- immunology #Humans #Interferon-gamma Release Tests -- methods #Latent Tuberculosis -- classification -- diagnosis #Lectins -- immunology #Retrospective Studies #Risk Assessment -- methods |
| Tipo |
info:eu-repo/semantics/article info:ulb-repo/semantics/articlePeerReview info:ulb-repo/semantics/openurl/article |
