Phenotypic characteristics of human type II alveolar epithelial cells suitable for antigen presentation to T lymphocytes.
| Data(s) |
2011
|
|---|---|
| Resumo |
Type II alveolar epithelial cells (AECII) are well known for their role in the innate immune system. More recently, it was proposed that they could play a role in the antigen presentation to T lymphocytes but contradictory results have been published both concerning their surface expressed molecules and the T lymphocyte responses in mixed lymphocyte cultures. The use of either AECII cell line or fresh cells could explain the observed discrepancies. Thus, this study aimed at defining the most relevant model of accessory antigen presenting cells by carefully comparing the two models for their expression of surface molecules necessary for efficient antigen presentation. Comparative Study Journal Article Research Support, Non-U.S. Gov't info:eu-repo/semantics/published |
| Formato |
1 full-text file(s): application/pdf |
| Identificador |
uri/info:doi/10.1186/1465-9921-12-15 uri/info:pii/1465-9921-12-15 uri/info:pmid/21261956 uri/info:pmcid/PMC3033824 https://dipot.ulb.ac.be/dspace/bitstream/2013/156559/1/PMC3033824.pdf http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/156559 |
| Idioma(s) |
en |
| Direitos |
1 full-text file(s): info:eu-repo/semantics/closedAccess |
| Fonte |
Respiratory research, 12 |
| Palavras-Chave | #Sciences bio-médicales et agricoles #Antigen Presentation #Antigen-Presenting Cells -- immunology #Antigens, CD -- metabolism #Cell Line, Tumor #Cells, Cultured #Flow Cytometry #HLA-DR Antigens -- metabolism #Humans #Immunophenotyping -- methods #Inflammation Mediators -- metabolism #Interferon-gamma -- metabolism #Phenotype #Pneumocytes -- immunology #T-Lymphocytes -- immunology #Tumor Necrosis Factor-alpha -- metabolism |
| Tipo |
info:eu-repo/semantics/article info:ulb-repo/semantics/articlePeerReview info:ulb-repo/semantics/openurl/article |
