Reduction of malaria prevalence by indoor residual spraying: a meta-regression analysis.
Data(s) |
01/07/2012
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Formato |
117 - 124 |
Identificador |
http://www.ncbi.nlm.nih.gov/pubmed/22764301 87/1/117 Am J Trop Med Hyg, 2012, 87 (1), pp. 117 - 124 http://hdl.handle.net/10161/6472 1476-1645 |
Relação |
Am J Trop Med Hyg 10.4269/ajtmh.2012.11-0620 http://hdl.handle.net/10161/6471 10161/6471 |
Tipo |
Journal Article |
Cobertura |
United States |
Resumo |
Indoor residual spraying (IRS) has become an increasingly popular method of insecticide use for malaria control, and many recent studies have reported on its effectiveness in reducing malaria burden in a single community or region. There is a need for systematic review and integration of the published literature on IRS and the contextual determining factors of its success in controlling malaria. This study reports the findings of a meta-regression analysis based on 13 published studies, which were chosen from more than 400 articles through a systematic search and selection process. The summary relative risk for reducing malaria prevalence was 0.38 (95% confidence interval = 0.31-0.46), which indicated a risk reduction of 62%. However, an excessive degree of heterogeneity was found between the studies. The meta-regression analysis indicates that IRS is more effective with high initial prevalence, multiple rounds of spraying, use of DDT, and in regions with a combination of Plasmodium falciparum and P. vivax malaria. |
Idioma(s) |
ENG |
Palavras-Chave | #Humans #Insecticides #Malaria #Prevalence #Regression Analysis |