Anti-beta(1)-adrenergic receptor antibodies and heart failure: causation, not just correlation.
| Data(s) |
01/05/2004
|
|---|---|
| Formato |
1379 - 1382 |
| Identificador |
http://www.ncbi.nlm.nih.gov/pubmed/15146232 J Clin Invest, 2004, 113 (10), pp. 1379 - 1382 0021-9738 |
| Relação |
J Clin Invest 10.1172/JCI21748 Journal of Clinical Investigation |
| Tipo |
Journal Article |
| Cobertura |
United States |
| Resumo |
Antibodies specific for the beta(1)-adrenergic receptor are found in patients with chronic heart failure of various etiologies. From work presented in this issue of the JCI, we can now infer that these antibodies actually contribute to the pathogenesis of chronic heart failure. This commentary discusses mechanisms by which these antibodies may engender cardiomyopathy. |
| Idioma(s) |
ENG |
| Palavras-Chave | #Adrenergic beta-Antagonists #Autoantibodies #Heart Failure #Humans #Models, Cardiovascular #Myocardium #Receptors, Adrenergic, beta-1 |
