Electrosprayed core-shell microspheres for protein delivery.


Autoria(s): Wu, Y; Liao, IC; Kennedy, SJ; Du, J; Wang, J; Leong, KW; Clark, RL
Data(s)

14/07/2010

Formato

4743 - 4745

Identificador

http://www.ncbi.nlm.nih.gov/pubmed/20485844

Chem Commun (Camb), 2010, 46 (26), pp. 4743 - 4745

http://hdl.handle.net/10161/4129

1364-548X

Idioma(s)

ENG

en_US

Relação

Chem Commun (Camb)

10.1039/c0cc00535e

Chemical Communications

Tipo

Journal Article

Cobertura

England

Resumo

This communication describes a single-step electrospraying technique that generates core-shell microspheres (CSMs) with encapsulated protein as the core and an amphiphilic biodegradable polymer as the shell. The protein release profiles of the electrosprayed CSMs showed steady release kinetics over 3 weeks without a significant initial burst.

Palavras-Chave #Kinetics #Microspheres #Polyesters #Polymers #Proteins