Biological rationale for regular physical exercise as an effective intervention for the prevention and treatment of depressive disorders


Autoria(s): Pareja Galeano, Helios; Mayero, Sara; Perales, María; Garatachea, Nuria; Santos-Lozano, Alejandro; Fiuza Luces, María del Carmen; Emanuele, Enzo; González Gálvez, Beatriz; Sanchís-Gomar, Fabián; Lucía Mulas, Alejandro
Data(s)

29/04/2016

29/04/2016

2016

Resumo

Depression is a major medical and social problem. Here we review current body of knowledge on the benefits of exercise as an effective strategy for both the prevention and treatment of this condition. We also analyze the biological pathways involved in such potential benefits, which include changes in neurotrophic factors, oxidative stress and inflammation, telomere length, brain volume and microvessels, neurotransmitters or hormones. We also identify major caveats in this field of research: further studies are needed to identify which are the most appropriate types of exercise interventions (intensity, duration, or frequency) to treat and prevent depression.

PI12/00914, SAF2015-67911

3.052 JCR (2015) Q2, 73/253 Pharmacology & pharmacy

UEM

Identificador

Pareja-Galeano, H. (2016). Biological rationale for regular physical exercise as an effective intervention for the prevention and treatment of depressive disorders. Current Pharmaceutical Design, 22(24), 3764-75.

13816128

http://hdl.handle.net/11268/5111

10.2174/1381612822666160322144537

Idioma(s)

eng

Direitos

openAccess

Palavras-Chave #Depresión mental #Enfermedad mental #Tratamiento médico #Tratamiento médico
Tipo

article