Amorphane sesquiterpenes from a marine Streptomyces sp.
Data(s) |
01/02/2007
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Resumo |
The chemical investigation of the crude extract of the marine-derived Streptomyces sp. M491 yielded three new sesquiterpenes, namely, 10 alpha,11-dihydroxyamorph-4-ene (4), 10 alpha,15-dihydroxyamorph-4-en-3-one (6), and 5 alpha,10 alpha,11-trihydroxyamorphan-3-one (7). In addition, the known compounds 10 alpha-hydroxyamorph-4-en-3-one (2), o-hydroxyacetanilide, genistein, prunetin, and indole-3-carbaldehyde and the macrolide antibiotic chalcomycin A were identified. The structures were determined on the basis of spectroscopic analysis, especially 1D and 2D NMR data. This is the first report of these sesquiterpenes from bacteria. The chemical investigation of the crude extract of the marine-derived Streptomyces sp. M491 yielded three new sesquiterpenes, namely, 10 alpha,11-dihydroxyamorph-4-ene (4), 10 alpha,15-dihydroxyamorph-4-en-3-one (6), and 5 alpha,10 alpha,11-trihydroxyamorphan-3-one (7). In addition, the known compounds 10 alpha-hydroxyamorph-4-en-3-one (2), o-hydroxyacetanilide, genistein, prunetin, and indole-3-carbaldehyde and the macrolide antibiotic chalcomycin A were identified. The structures were determined on the basis of spectroscopic analysis, especially 1D and 2D NMR data. This is the first report of these sesquiterpenes from bacteria. |
Identificador | |
Idioma(s) |
英语 |
Fonte |
Wu, Shao Jie; Fotso, Serge; Li, Fuchao; Qin, Song; Laatsch, Hartmut.Amorphane sesquiterpenes from a marine Streptomyces sp.,JOURNAL OF NATURAL PRODUCTS,2007,70(2):304-306 |
Palavras-Chave | #Plant Sciences; Chemistry, Medicinal; Pharmacology & Pharmacy #CADINANE-TYPE SESQUITERPENES |
Tipo |
期刊论文 |