Determination of propranolol by capillary electrophoresis with end-column amperometric detection
Data(s) |
2000
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Resumo |
A capillary electrophoresis-amperometric detection system was developed for the determination of propranolol (PRO) at a 33 mu m carbon fiber microdisk electrode (CFE). The cyclic voltammogram, the hydrodynamic voltammograms and the effect of pH were studied. Under the optimum conditions: separation Voltage 15 kV; injection 3 s at 15 kV; 10 mM pH 7.5 phosphate buffer, 1.15 V (vs. Ag/AgCl) detection potential, the detection limit (LOD) for PRO was 0.05 mu M (S/N = 3). The response for PRO was linear over two orders of magnitude with a linear correlation coefficient of 0.994. The feasibility of this method was demonstrated by the detection of PRO in urine sample. |
Identificador | |
Idioma(s) |
英语 |
Fonte |
Bai XX;You TY;Sun HW;Yang XR;Wang EK.Determination of propranolol by capillary electrophoresis with end-column amperometric detection,ELECTROANALYSIS,2000,12(7):535-537 |
Palavras-Chave | #IMPROVED CHIRAL SEPARATION #GAS-CHROMATOGRAPHY #BETA-BLOCKERS #ATENOLOL #CYCLODEXTRIN #SPECTROMETRY #METOPROLOL #REAGENTS |
Tipo |
期刊论文 |