A study of isomeric diglycosyl flavonoids by SORI CID of Fourier transform ion cyclotron mass Spectrometry in negative ion mode


Autoria(s): Yan CY; Liu SY; Zhou YH; Song FR; Cui M; Liu ZQ
Data(s)

2007

Resumo

High-resolution Sustained off resonance irradiation (SORI) CID was employed to distinguish four pairs of isomeric diglycosyl flavonoids in the negative mode using the electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry (ESI FTICR MS). All of these isomers can be distinguished via MS/MS data. For these diglycosyl flavones and flavanones, the deprotonated alpha 1-->6 linkage diglycosyl flavonoids produce fewer fragments than the alpha 1-->2 linkage type compounds and the Retro-Diels-Alder (RDA) reaction in MS/MS only takes place when the aglycone is a flavanone and glycosylated with an alpha 1-->2 intersaccharide linkage disaccharide. The deprotonation sites after collisional activation are discussed according to the high mass accuracy and high-resolution data of tandem spectrometry. Some of these high-resolution SORI CID product ions from alpha 1-->2 linkage diglycosyl flavonoids involve multibond cleavages; the possible mechanism is discussed based on the computer modeling using Gaussian 03 program package at the B3LYP/6-31G level of theory. Unambiguous elementary composition data provides fragmentation information that has not been reported previously.

Identificador

http://ir.ciac.jl.cn/handle/322003/13409

http://www.irgrid.ac.cn/handle/1471x/149204

Idioma(s)

英语

Fonte

Yan CY;Liu SY;Zhou YH;Song FR;Cui M;Liu ZQ.A study of isomeric diglycosyl flavonoids by SORI CID of Fourier transform ion cyclotron mass Spectrometry in negative ion mode,JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY,2007 ,18(12):2127-2136

Palavras-Chave #FRAGMENTATION #DISSOCIATION #TRAP
Tipo

期刊论文