Apoptotic cells induce immunosuppression through dendritic cells: Critical roles of IFN-gamma and nitric oxide

Apoptotic cells induce immunosuppression through unknown mechanisms. To identify the underlying molecular mediators, we examined how apoptotic cells induce immunoregulation by dendritic cells (DC). We found that administration of DC exposed to apoptotic c

This work was supported in part by New Jersey Commission on Science and Technology (NJCST-2042-014-84), United States Public Health Service Grants (AI057596 and AI50222), and the National Space Biomedical Research Institute (IIH00405), which is supported