Evidence of gene conversion in the evolutionary process of the codon 41/42 (-CTTT) mutation causing beta-thalassemia in southern China


Autoria(s): Zhang, W; Cai, WW; Zhou, WP; Li, HP; Li, L; Yan, W; Deng, QK; Zhang, YP; Fu, YX; Xu, XM
Data(s)

2008

Resumo

The 4-bp deletion (-CTTT) at codon 41/42 (CD41/42) of the human beta-globin gene represents one of the most common beta-thalassemia mutations in East Asia and Southeast Asia, which is historically afflicted with endemic malaria, thus hypothetically evolvi

Identificador

http://159.226.149.42:8088/handle/152453/4289

http://www.irgrid.ac.cn/handle/1471x/47442

Direitos

Evidence of gene conversion in the evolutionary process of the codon 41/42 (-CTTT) mutation causing beta-thalassemia in southern China

Fonte

Zhang, W; Cai, WW; Zhou, WP; Li, HP; Li, L; Yan, W; Deng, QK; Zhang, YP; Fu, YX; Xu, XM.Evidence of gene conversion in the evolutionary process of the codon 41/42 (-CTTT) mutation causing beta-thalassemia in southern China,66,436-445,(SCI-E ):

Palavras-Chave #Biochemistry & Molecular Biology; Evolutionary Biology; Genetics & Heredity
Tipo

期刊论文