Catalytic Asymmetric Direct Vinylogous Michael Addition of gamma-Aryl-Substituted Deconjugated Butenolides to Nitroolefins and N-Phenylmaleimide
Data(s) |
2013
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Resumo |
Direct asymmetric vinylogous Michael reactions of gamma-aryl-substituted deconjugated butenolides with nitroolefins and N-phenylmaleimide are described using bifunctional thiourea derivatives as the catalyst. The resulting butenolide derivatives containing adjacent quaternary and tertiary stereocenters are obtained in good yields (54-90%) and with excellent enantioselectivities (er up to 99:1) and high diastereoselectivities (dr up to > 20:1). |
Formato |
application/pdf |
Identificador |
http://eprints.iisc.ernet.in/47074/1/syn_stu_45-12_1641_2013.pdf Kumar, Vikas and Ray, Bidisha and Rathi, Preeti and Mukherjee, Santanu (2013) Catalytic Asymmetric Direct Vinylogous Michael Addition of gamma-Aryl-Substituted Deconjugated Butenolides to Nitroolefins and N-Phenylmaleimide. In: SYNTHESIS-STUTTGART, 45 (12). pp. 1641-1646. |
Publicador |
GEORG THIEME VERLAG KG |
Relação |
http://dx.doi.org/10.1055/s-0033-1338705 http://eprints.iisc.ernet.in/47074/ |
Palavras-Chave | #Organic Chemistry |
Tipo |
Journal Article PeerReviewed |