Formal total synthesis of (+)-didemniserinolipid B
Data(s) |
08/12/2010
|
---|---|
Resumo |
The formal total synthesis of (+)-didemniserinolipid B, a marine tunicate possessing a 6,8-dioxabicyclo3.2.1]octane framework, was accomplished starting from L-(+)-tartaric acid. The key transformations in the synthesis include the elaboration of a gamma-hydroxy-amide readily obtained by desymmetrization of tartaric acid bis-amide via the controlled addition of a Grignard reagent followed by stereoselective reduction of the resulting ketone. (C) 2010 Elsevier Ltd. All rights reserved. |
Formato |
application/pdf |
Identificador |
http://eprints.iisc.ernet.in/35965/1/Formal.pdf Prasad, Kavirayani R and Gandi, Vasudeva Rao (2010) Formal total synthesis of (+)-didemniserinolipid B. In: Tetrahedron: Asymmetry, 21 (23). pp. 2848-2852. |
Publicador |
Elsevier Science |
Relação |
http://dx.doi.org/10.1016/j.tetasy.2010.11.006 http://eprints.iisc.ernet.in/35965/ |
Palavras-Chave | #Organic Chemistry |
Tipo |
Journal Article PeerReviewed |