Optical tweezer for probing erythrocyte membrane deformability


Autoria(s): Khan, Manas; Soni, Harsh; Sood, AK
Data(s)

07/12/2009

Resumo

We report that the average rotation speed of optically trapped crenated erythrocytes is direct signature of their membrane deformability. When placed in hypertonic buffer, discocytic erythrocytes are subjected to crenation. The deformation of cells brings in chirality and asymmetry in shape that makes them rotate under the scattering force of a linearly polarized optical trap. A change in the deformability of the erythrocytes, due to any internal or environmental factor, affects the rotation speed of the trapped crenated cells. Here we show how the increment in erythrocyte membrane rigidity with adsorption of Ca++ ions can be exhibited through this approach.

Formato

application/pdf

Identificador

http://eprints.iisc.ernet.in/25349/1/12.pdf

Khan, Manas and Soni, Harsh and Sood, AK (2009) Optical tweezer for probing erythrocyte membrane deformability. In: Applied physics letters, 95 (23).

Publicador

American Institute of Physics

Relação

http://scitation.aip.org/getabs/servlet/GetabsServlet?prog=normal&id=APPLAB000095000023233703000001&idtype=cvips&gifs=yes

http://eprints.iisc.ernet.in/25349/

Palavras-Chave #Physics
Tipo

Journal Article

PeerReviewed