3D QSAR studies of N-4-arylacryloylpiperazin-1-yl-phenyl-oxazolidinones: A novel class of antibacterial agents
| Data(s) |
15/07/2006
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|---|---|
| Resumo |
Three-dimensional QSAR studies for N-4-arylacryloylpiperazin-1-yl-phenyl-oxazolidinones were conducted using TSAR 3.3. The in vitro activities (MICs) of the compounds against Staphylococcus aureus ATCC 25923 exhibited a strong correlation with the prediction made by the model developed in the present study. |
| Identificador | |
| Publicador |
Elsevier Ltd. |
| Relação |
DOI:10.1016/j.bmcl.2006.04.023 Lohray, B. B., Gandhi, Neha, Srivastava, Brijesh Kumar, & Lohray, Vidya Bhushan (2006) 3D QSAR studies of N-4-arylacryloylpiperazin-1-yl-phenyl-oxazolidinones: A novel class of antibacterial agents. Bioorganic and Medicinal Chemistry Letters, 16(14), pp. 3817-3823. |
| Direitos |
Copyright 2006 Elsevier Ltd. |
| Fonte |
School of Mathematical Sciences; Science & Engineering Faculty |
| Palavras-Chave | #3D QSAR; In vitro MIC; Heat of formation; LUMO; Antibacterial agent; Arylacryloylpiperazinylphenyloxazolidinones |
| Tipo |
Journal Article |
