Inhibition of Peroxidase-Catalyzed Iodination by Cephalosporins: Metallo-beta-Lactamase-Induced Antithyroid Activity of Antibiotics
| Data(s) |
01/04/2009
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|---|---|
| Resumo |
Broad-spectrum antibiotics with heterocyclic side chains strongly inhibit peroxidase-catalyzed iodination in the presence of metallo--lactamase. This suggests that antibiotic resistance due to hydrolysis of the -lactam ring in antibiotics would have negative effects on thyroid activity. |
| Formato |
application/pdf |
| Identificador |
http://eprints.iisc.ernet.in/20436/1/fulltext.pdf Tamilselvi, A and Mugeshii, Govindasamy (2009) Inhibition of Peroxidase-Catalyzed Iodination by Cephalosporins: Metallo-beta-Lactamase-Induced Antithyroid Activity of Antibiotics. In: ChemMedChem, 4 (4). pp. 512-516. |
| Publicador |
John Wiley and Sons |
| Relação |
http://www3.interscience.wiley.com/journal/121583408/abstract http://eprints.iisc.ernet.in/20436/ |
| Palavras-Chave | #Inorganic & Physical Chemistry |
| Tipo |
Journal Article PeerReviewed |
