Chemical Modification Studies of Gelonin - Involvement of Arginine Residues in Biological-Activity


Autoria(s): Srinivasan, Y; Ramprasad, MP; Surolia, A
Data(s)

1985

Resumo

Gelonin inhibits protein synthesis by inactivating the eukaryotic 60 S ribosomal subunit by an unknown mechanism. The protein was purified in high yield by a new method using Cibacron blue F3GA-Sepharose. Chemical modification studies reveal that arginine residues are essential for biological activity.

Formato

application/pdf

Identificador

http://eprints.iisc.ernet.in/20150/1/pdf.pdf

Srinivasan, Y and Ramprasad, MP and Surolia, A (1985) Chemical Modification Studies of Gelonin - Involvement of Arginine Residues in Biological-Activity. In: FEBS Letters, 192 (1). pp. 113-118.

Publicador

Elsevier Science

Relação

http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T36-44DT1M2-DW&_user=512776&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000025298&_version=1&_urlVersion=0&_userid=512776&md5=ff5320be7c1a06d80c0a1991fdbba521

http://eprints.iisc.ernet.in/20150/

Palavras-Chave #Molecular Biophysics Unit
Tipo

Journal Article

PeerReviewed