Early detection of melanoma metastases using microRNAs as novel biomarkers


Autoria(s): Stark, Mitchell S.
Data(s)

2015

Resumo

Early detection of melanoma skin cancer, prior to metastatic spread, is critical to improve survival outcomes in patients. This study identified a melanoma-related panel of blood markers that can detect the presence of melanoma with high sensitivity and accuracy which is superior to currently used markers for melanoma progression, recurrence, and survival. Overall, the findings discussed in this thesis may lead to more precise measurement of disease progression allowing for better treatments and an increase in overall survival.

Formato

application/pdf

Identificador

http://eprints.qut.edu.au/90041/

Publicador

Queensland University of Technology

Relação

http://eprints.qut.edu.au/90041/8/Mitchell_Stark_Thesis.pdf

Stark, Mitchell S. (2015) Early detection of melanoma metastases using microRNAs as novel biomarkers. PhD by Publication, Queensland University of Technology.

Fonte

School of Biomedical Sciences; Faculty of Health; Institute of Health and Biomedical Innovation

Palavras-Chave #Melanoma #miRNA #microRNA #biomarker #progression #resistance #NF1 #miR-514a #miR-4731
Tipo

Thesis