Ethyl 1-(2-cyanoethyl)-3,5-dimethyl-1H-indole-2-carboxylate


Autoria(s): Chandrakantha, TN; Puttaraja, *; Kokila, MK; Shivaprakash, NC
Data(s)

15/06/1999

Resumo

The title compound, C16H18N2O2, is an important precursor in the synthesis of 1,2,3,4-tetrahydropyrazinoindoles, which show excellent antihistamine, antihypertensive and central nervous system depressant properties. The carbethoxy group attached to C2 and the planar cyanoethyl group attached to N1 make dihedral angles of 11.0(4) and 75.0(3)degrees, respectively, with the mean plane of the indole ring, The C-C=N chain is linear with a bond angle of 179.3 (4)degrees.

Formato

application/pdf

Identificador

http://eprints.iisc.ernet.in/19292/1/da1055.pdf

Chandrakantha, TN and Puttaraja, * and Kokila, MK and Shivaprakash, NC (1999) Ethyl 1-(2-cyanoethyl)-3,5-dimethyl-1H-indole-2-carboxylate. In: Acta Crystallographica Section C-Crystal Structure Communications, 55 (6). pp. 990-992.

Publicador

International Union of Crystallography

Relação

http://scripts.iucr.org/cgi-bin/paper?S0108270199001973

http://eprints.iisc.ernet.in/19292/

Palavras-Chave #Instrumentation and Applied Physics (Formally ISU)
Tipo

Journal Article

PeerReviewed