Genetics of ankylosing spondylitis


Autoria(s): Brown, M.A.; Wordsworth, B.P.; Reveille, J. D.
Data(s)

2002

Resumo

Ankylosing spondylitis is a common inflammatory rheumatic disease. Both susceptibility to and clinical manifestations of the disease are highly heritable. Although some genes, notably HLA-B27, have been implicated in susceptibility to the disease, the genetics of the condition are complex and many more genes involved in the condition await discovery.

Identificador

http://eprints.qut.edu.au/87989/

Publicador

Clinical and Experimental Rheumatology Sas

Relação

http://www.scopus.com/inward/record.url?eid=2-s2.0-0036399587&partnerID=40&md5=30e734917b2daa18240e2b7b694fffa6

Brown, M.A., Wordsworth, B.P., & Reveille, J. D. (2002) Genetics of ankylosing spondylitis. Clinical and Experimental Rheumatology, 20(6SUP28), S43-S49.

Fonte

School of Biomedical Sciences; Faculty of Health; Institute of Health and Biomedical Innovation

Palavras-Chave #Ankylosing spondylitis #Association #Genetics #HLA #Linkage #Spondyloarthritis #HLA B27 antigen #HLA B60 antigen #HLA DR antigen #tumor necrosis factor alpha #HLA-DRB1 antigen #article #controlled study #disease severity #familial disease #gene linkage disequilibrium #gene mapping #genetic epidemiology #genetic linkage #genetic risk #genetic susceptibility #heredity #human #immunogenetics #priority journal #rheumatic disease #chromosome map #hospitalization #major histocompatibility complex #pathophysiology #review #Chromosome Mapping #HLA-B27 Antigen #HLA-DR Antigens #Humans #Severity of Illness Index #Spondylitis #Ankylosing
Tipo

Journal Article