ERAP2 is associated with ankylosing spondylitis in HLA-B27-positive and HLA-B27-negative patients
| Data(s) |
01/08/2015
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| Resumo |
The association of endoplasmic reticulum aminopeptidase 2 (ERAP2) with ankylosing spondylitis (AS) was recently described in the large International Genetics of AS Consortium Immunochip study... |
| Identificador | |
| Publicador |
BMJ Publishing Group |
| Relação |
DOI:10.1136/annrheumdis-2015-207416 Robinson, P. C., Costello, M. E., Leo, P., Bradbury, L. A., Hollis, K., Cortes, A., Lee, S., Joo, K. B., Shim, S. C., Weisman, M., Ward, M., Zhou, X., Garchon, H. J., Chiocchia, G., Nossent, J., Lie, B. A., Førre, Ø, Tuomilehto, J., Laiho, K., Jiang, L., Liu, Y., Wu, X., Elewaut, D., Burgos-Vargas, R., Gensler, L. S., Stebbings, S., Haroon, N., Mulero, J., Fernandez-Sueiro, J. L., Gonzalez-Gay, M. A., Lopez-Larrea, C., Bowness, P., Gafney, K., Gaston, J. S. H., Gladman, D. D., Rahman, P., Maksymowych, W. P., Xu, H., Van Der Horst-Bruinsma, I. E., Chou, C. T., Valle-Oñate, R., Romero-Sánchez, M. C., Hansen, I. M., Pimentel-Santos, F. M., Inman, R. D., Martin, J., Breban, M., Evans, D., Reveille, J. D., Kim, T. H., Wordsworth, B. P., & Brown, Matthew A. (2015) ERAP2 is associated with ankylosing spondylitis in HLA-B27-positive and HLA-B27-negative patients. Annals of the Rheumatic Diseases, 74(8), pp. 1627-1629. |
| Fonte |
School of Biomedical Sciences; Institute of Health and Biomedical Innovation |
| Palavras-Chave | #aminopeptidase #endoplasmic reticulum aminopeptidase 1 #endoplasmic reticulum aminopeptidase 2 #HLA B27 antigen #unclassified drug #ankylosing spondylitis #enzyme mechanism #enzyme specificity #ERAP1 gene #ERAP2 gene #gene #gene dosage #gene interaction #gene linkage disequilibrium #genetic association #haplotype #HLA B27 gene #human #Letter #pathogenesis #priority journal #protein expression #single nucleotide polymorphism |
| Tipo |
Journal Article |
