Matters Arising: Zhu et al, "A novel gene variation of TNFα associated with ankylosing spondylitis: A reconfirmed study"


Autoria(s): Brown, M A
Data(s)

01/03/2008

Resumo

In a recently published study1 involving 79 ankylosing spondylitis (AS) patients and 132 unrelated healthy blood donors, Zhu et al report association of a tumour necrosis factor α (TNFα) single nucleotide polymorphism (SNP), rs1799724, with AS.1 I have many concerns with this paper and its conclusions...

Identificador

http://eprints.qut.edu.au/87726/

Publicador

BMJ Publishing Group

Relação

http://ard.bmj.com/content/67/3/434.1.full

Brown, M A (2008) Matters Arising: Zhu et al, "A novel gene variation of TNFα associated with ankylosing spondylitis: A reconfirmed study". Annals of the Rheumatic Diseases, 67(3), p. 434.

Fonte

School of Biomedical Sciences; Institute of Health and Biomedical Innovation

Palavras-Chave #biological marker #HLA B antigen #HLA B27 antigen #HLA B60 antigen #tumor necrosis factor alpha #allele #ankylosing spondylitis #blood donor #clinical study #gene linkage disequilibrium #genetic association #genetic variability #genotype #heterozygosity #homozygosity #human #letter #major histocompatibility complex #medical error #priority journal #single nucleotide polymorphism #genetic predisposition #genetics #note #Genetic Predisposition to Disease #Humans #Linkage Disequilibrium #Polymorphism #Single Nucleotide #Spondylitis #Ankylosing #Tumor Necrosis Factor-alpha
Tipo

Journal Article