Multimodal imaging of the collagen and elastic fibre networks in the bovine intervertebral disc
Contribuinte(s) |
Freeman, Brian J. |
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Data(s) |
14/08/2014
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Resumo |
INTRODUCTION. The intervertebral disc is the largest avascular structure in the human body, withstanding transient loads of up to nine times body weight during rigorous physical activity. The key structural elements of the disc are a gel-like nucleus pulposus surrounded by concentric lamellar rings containing criss-crossed collagen fibres. The disc also contains an elastic fiber network which has been suggested to play a structural role, but to date the relationship between the collagen and elastic fiber networks is unclear. CONCLUSION. The multimodal transmitted and reflected polarized light microscopy technique developed here allows clear differentiation between the collagen and elastic fiber networks of the intervertebral disc. The ability to image unstained specimens avoids concerns with uneven stain penetration or specificity of staining. In bovine tail discs, the elastic fiber network is intimately associated with the collagen network. |
Formato |
application/pdf |
Identificador | |
Relação |
http://eprints.qut.edu.au/87659/1/2014%20ACSR%20IVD%20multimodal%20imaging%20ePrints.pdf Adam, Clayton, Rouch, Philippe, & Skalli, Wafa (2014) Multimodal imaging of the collagen and elastic fibre networks in the bovine intervertebral disc. In Freeman, Brian J. (Ed.) The Adelaide Centre for Spinal Research - Spinal Research Symposium XII, 14-16 August 2014, Hilton Hotel, Adelaide, SA. (Unpublished) |
Direitos |
Copyright 2014 The Authors |
Fonte |
School of Chemistry, Physics & Mechanical Engineering; Institute of Health and Biomedical Innovation; Science & Engineering Faculty |
Palavras-Chave | #090302 Biomechanical Engineering #110314 Orthopaedics #bovine disc #multimodal imaging #intervertebral disc #disc lamellae #polarized light microscopy #elastin fibres #collagen network |
Tipo |
Conference Item |