Identification of genetic variants contributing to the migraine phenotype in different Australian populations
Data(s) |
2015
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Resumo |
This project aimed to identify novel genetic risk variants associated with migraine in the Norfolk Island population. Statistical analysis and bioinformatics approaches such as polygenic modeling and gene clustering methods were carried out to explore genotypic and expression data from high-throughput techniques. This project had a particular focus on hormonal genes and other genetic variants and identified a modest effect size on the migraine phenotype. |
Formato |
application/pdf |
Identificador | |
Publicador |
Queensland University of Technology |
Relação |
http://eprints.qut.edu.au/87082/1/Astrid%20Jannet_Rodriguez%20Acevedo_Thesis.pdf Rodriguez Acevedo, Astrid Jannet (2015) Identification of genetic variants contributing to the migraine phenotype in different Australian populations. PhD by Publication, Queensland University of Technology. |
Fonte |
School of Biomedical Sciences; Faculty of Health; Institute of Health and Biomedical Innovation |
Palavras-Chave | #Migraine #Menstrual Migraine #Norfolk Island Population #ESR1 #TNF #Genetic Risk Score #Clustering Analysis #Association studies #eQTL analysis |
Tipo |
Thesis |