Fibroin-based materials support co-cultivation of limbal epithelial and stromal cells


Autoria(s): Bray, L.J.; George, K.A.; Hutmacher, D.W.; Chirila, T.V.; Harkin, D.G.
Data(s)

2011

Resumo

The silk protein fibroin (Bombyx mori) provides a potential substrate for use in ocular tissue reconstruction. We have previously demonstrated that transparent membranes produced from fibroin support cultivation of human limbal epithelial (HLE) cells (Tissue Eng A. 14(2008)1203-11). We extend this body of work to studies of human limbal stromal cell (HLS) growth on fibroin in the presence and absence of serum. Also, we investigate the ability to produce a bi-layered composite scaffold of fibroin with an upper HLE layer and lower HLS layer.

Formato

application/pdf

Identificador

http://eprints.qut.edu.au/82953/

Relação

http://eprints.qut.edu.au/82953/1/Bray%20et%20al%202011%20Histol%20Histopathol%20p346.pdf

Bray, L.J., George, K.A., Hutmacher, D.W., Chirila, T.V., & Harkin, D.G. (2011) Fibroin-based materials support co-cultivation of limbal epithelial and stromal cells. In Tissue Engineering and Regenerative Medicine International Society European Meeting, 7-10 June 2011, Granada, Spain.

Direitos

Copyright 2011 [Please consult the author]

Fonte

School of Biomedical Sciences; Faculty of Health; Institute of Health and Biomedical Innovation

Tipo

Conference Item