Identification of broad specificity P450CAM variants by primary screening against indole as substrate


Autoria(s): Çelik, Ayhan; Speight, Robert E.; Turner, Nicholas J.
Data(s)

2005

Resumo

High-throughput screening of cytochrome P450CAM libraries, for their ability to oxidise indole to indigo and indirubin, has resulted in the identification of variants with activity towards the structurally unrelated substrate diphenylmethane.

Formato

application/pdf

Identificador

http://eprints.qut.edu.au/70982/

Publicador

Royal Society of Chemistry

Relação

http://eprints.qut.edu.au/70982/1/70982.pdf

DOI:10.1039/B506156C

Çelik, Ayhan, Speight, Robert E., & Turner, Nicholas J. (2005) Identification of broad specificity P450CAM variants by primary screening against indole as substrate. Chemical Communications, 29, p. 3652.

Direitos

Copyright 2005 Royal Society of Chemistry

Fonte

School of Chemistry, Physics & Mechanical Engineering; Science & Engineering Faculty

Tipo

Journal Article