Preparation of mesoporous bioglass coated zirconia scaffold for bone tissue engineering
Data(s) |
2012
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Resumo |
Porous yttria-stabilized zirconia (YSZ) has been regarded as a potential candidate for bone substitute due to its high mechanical strength. However, porous YSZ is biologically inert to bone tissue. It is therefore necessary to introduce bioactive coatings onto the walls of the porous structures to enhance its bioactivity. In this study, porous YSZ scaffolds were prepared using a replication technique and then coated with mesoporous bioglass due to its excellent bioactivity. The microstructures were examined using scanning electron microscopy and the mechanical strength was evaluated via compression test. The biocompatibility and bioactivity were also evaluated using bone marrow stromal cell (BMSC) proliferation test and simulated body fluid test. |
Formato |
application/pdf |
Identificador | |
Publicador |
Trans Tech Publications Ltd. |
Relação |
http://eprints.qut.edu.au/70146/1/cmbb2010_submission_1010.pdf http://www.ttp.net/1022-6680.html Lin, Feng, Yan, Cheng, Zheng, Wei, Fan, Wei, Adam, Clayton, & Oloyede, Adekunle (2012) Preparation of mesoporous bioglass coated zirconia scaffold for bone tissue engineering. Advanced Materials Research, 365, pp. 209-215. |
Direitos |
Copyright 2011 Trans Tech Publications Ltd. |
Fonte |
School of Chemistry, Physics & Mechanical Engineering; Faculty of Built Environment and Engineering; Science & Engineering Faculty |
Palavras-Chave | #091201 Ceramics #091299 Materials Engineering not elsewhere classified #scaffold #porous structure #mesoporous bioglass #zirconia #compressive strength #porous materials #mechanical strength |
Tipo |
Journal Article |