Recent advances in the design of artificial corneas
Data(s) |
01/05/2014
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Resumo |
Purpose of review: Artificial corneas are being developed to meet a shortage of donor corneas as well as to address cases where allografting is contraindicated. A range of artificial corneas has been developed. Here we review several newer designs and especially those inspired by naturally occurring biomaterials found with the human body and elsewhere. Recent findings: Recent trends in the development of artificial corneas indicate a move towards the use of materials derived from native sources including decellularized corneal tissue and tissue substitutes synthesized by corneal cells in vitro when grown either on their own, or in conjunction with novel protein-based scaffolds. Biologically inspired materials are also being considered for implantation on their own with the view to promoting endogenous corneal tissue. Summary: More recent attempts at making artificial corneas have taken a more nature-based or nature-inspired approach. Several will in the near future be likely to be available clinically. |
Formato |
application/pdf |
Identificador | |
Publicador |
Lippincott, Williams & Wilkins |
Relação |
http://eprints.qut.edu.au/67415/1/Griffith_and_Harkin_accepted_ver.pdf DOI:10.1097/ICU.0000000000000049 Griffith, May & Harkin, Damien G. (2014) Recent advances in the design of artificial corneas. Current Opinion in Ophthalmology, 25(3), pp. 240-247. |
Direitos |
Copyright 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins This is a non-final version of an article published in final form in Current Opinion in Ophthalmology, 25(3):240-247, May 2014 |
Fonte |
School of Biomedical Sciences; Faculty of Health; Institute of Health and Biomedical Innovation |
Palavras-Chave | #090301 Biomaterials #100404 Regenerative Medicine (incl. Stem Cells and Tissue Engineering) #111301 Ophthalmology #Cornea #Tissue engineering #Artificial cornea #Regenerative medicine #Biomaterials |
Tipo |
Journal Article |