RANKL expression in periodontal disease : where does RANKL come from?
| Data(s) |
2014
|
|---|---|
| Resumo |
Periodontitis is an inflammatory disease characterized by periodontal pocket formation and alveolar bone resorption. Periodontal bone resorption is induced by osteoclasts and receptor activator of nuclear factor-κB ligand (RANKL) which is an essential and central regulator of osteoclast development and osteoclast function. Therefore, RANKL plays a critical role in periodontal bone resorption. In this review, we have summarized the sources of RANKL in periodontal disease and explored which factors may regulate RANKL expression in this disease. |
| Formato |
application/pdf |
| Identificador | |
| Publicador |
Hindawi Publishing Corporation |
| Relação |
http://eprints.qut.edu.au/66705/1/2014_Fuhua_Yin_BioMed_Research_International.pdf http://www.hindawi.com/journals/bmri/aip/731039/ DOI:10.1155/2014/731039 Chen, Bin, Wu, Wenlei, Sun, Weibin, Zhang, Qian, Yan, Fuhua, & Xiao, Yin (2014) RANKL expression in periodontal disease : where does RANKL come from? BioMed Research International, 2014(731039). |
| Direitos |
Copyright 2014 Bin Chen et al. This is an open access article distributed under theCreativeCommonsAttribution License,which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| Fonte |
Institute of Health and Biomedical Innovation; Science & Engineering Faculty |
| Palavras-Chave | #060000 BIOLOGICAL SCIENCES #110500 DENTISTRY #Receptor activator of nuclear factor-κB ligand (RANKL) #Periodontal disease #Bone resorption |
| Tipo |
Journal Article |
