Gene silencing as an adaptive defence against viruses
Data(s) |
2001
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Resumo |
Gene silencing was perceived initially as an unpredictable and inconvenient side effect of introducing transgenes into plants. It now seems that it is the consequence of accidentally triggering the plant's adaptive defence mechanism against viruses and transposable elements. This recently discovered mechanism, although mechanistically different, has a number of parallels with the immune system of mammals. |
Identificador | |
Publicador |
Nature Publishing Group |
Relação |
DOI:10.1038/35081168 Waterhouse, P. M., Wang, M. B., & Lough, T. (2001) Gene silencing as an adaptive defence against viruses. Nature, 411(6839), pp. 834-842. |
Direitos |
Nature Publishing Group |
Fonte |
School of Earth, Environmental & Biological Sciences; Science & Engineering Faculty |
Palavras-Chave | #adaptation #gene silencing #immune system #infection resistance #nonhuman #plant #priority journal #review #RNA degradation #transgene #transposon #virus infection #Animals #DNA Transposable Elements #Gene Expression Regulation #Plant #Methylation #Plant Diseases #Plant Viruses #Plants #Ribonucleases #RNA #Antisense #RNA #Small Interfering #RNA #Viral #Mammalia |
Tipo |
Journal Article |