The role of vascular and hormonal genes in migraine susceptibility
Data(s) |
2006
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Resumo |
Migraine is a primary headache disorder that involves both genetic and environmental components. Migraine is considered to be a polygenic disorder with a number of susceptibility genes having a minor but nonetheless significant impact on susceptibility. Migraine candidate gene studies have concentrated mainly on genes involved in neurotransmitter pathways, however evidence also exists for a role for alterations in vascular and hormonal function in migraine susceptibility. We present here a mini-review of genetic studies, investigating the potential role of vascular and hormonal gene variants, and discuss how vascular and hormonal dysfunction may impact on migraine susceptibility. We propose that the potential role of vascular and hormonal genes in this disorder warrants further investigation. |
Identificador | |
Publicador |
Academic Press |
Relação |
DOI:10.1016/j.ymgme.2005.11.013 Colson, Natalie J., Lea, Rod A., Quinlan, Sharon, & Griffiths, Lyn R. (2006) The role of vascular and hormonal genes in migraine susceptibility. Molecular Genetics and Metabolism, 88(2), pp. 107-113. |
Direitos |
Copyright 2006 Academic Press |
Fonte |
Faculty of Health; Institute of Health and Biomedical Innovation |
Tipo |
Journal Article |